DAB2IP

Also known as AF9Q34, AIP-1, AIP1, DIP1/2, DAB2 interacting protein

Disabled homolog 2-interacting protein is a protein that in humans is encoded by the DAB2IP gene.

In the Vinony graph

Within Vinony's link graph, DAB2IP is referenced by 5 other articles, and connects out to PubMed, human chromosome 9 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 9.

Its subject is documented across 5 Wikipedia language editions.

Gene data

DAB2IP

Name: DAB2 interacting protein
Type: protein-coding
Position: 121,567,057–121,785,530 (+)
Aliases: AF9Q34, AIP-1, AIP1, DIP1/2
Ensembl: ENSG00000136848
RefSeq RNA: NM_001395010.1, NM_032552.4, NM_138709.2
RefSeq protein: NP_001381939.1, NP_115941.2, NP_619723.1

DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor. The DAB2IP gene is inactivated by methylation in prostate and breast cancers (Yano et al., 2005 [PubMed 15386433]).[supplied by OMIM, May 2010].

Pathways

Apoptosis - Homo sapiens (human)TNF signaling pathway - Homo sapiens (human)Signal Transduction Regulation of RAS by GAPs RAF/MAP kinase cascade MAPK family signaling cascades MAPK1/MAPK3 signaling Ebola Virus Pathway on Host

via MyGene.info

Gene · Ensembl

DAB2 interacting protein

Symbol: DAB2IP
Biotype: Protein coding
Organism: Homo sapiens
Location: 9:121,567,057-121,785,530
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 9 more facts

HomoloGene ID: 13058
genetic association: abdominal aortic aneurysm
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/153090
genomic end: 124547809
genomic start: 124329336
chromosome: human chromosome 9
cytogenetic location: 9q33.2
expressed in: ascending aorta

Sources (5)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

Interactions
References
Further reading

Disabled homolog 2-interacting protein is a protein that in humans is encoded by the DAB2IP gene.

DAB2IP is a Ras (MIM 190020) GTPase-activating protein (GAP) that acts as a tumor suppressor gene and is inactivated by methylation in prostate and breast cancers (Yano et al., 2005).[supplied by OMIM]

Excerpted from Wikipedia’s “DAB2IP” article, available under the CC BY-SA 4.0 licence.