Structure via PubChem · Public domain (PubChem)
exatecan
Sign in to saveExatecan is a drug which is a structural analog of camptothecin with antineoplastic activity.
In the Vinony graph
Within Vinony's link graph, exatecan is referenced by 276 other articles, and connects out to tiazofurin, medication and digital object identifier.
It sits within the topics Amines, Chembox image size set and Chemical articles with multiple compound IDs.
Its subject is documented across 8 Wikipedia language editions.
Chemical data
- Formula
- C24H22FN3O4
- Molecular weight
- 435.4 g/mol
- IUPAC name
- (10S,23S)-23-amino-10-ethyl-18-fluoro-10-hydroxy-19-methyl-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaene-5,9-dione
- SMILES
- CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O
- InChIKey
- ZVYVPGLRVWUPMP-FYSMJZIKSA-N
- XLogP
- 0.4
- Polar surface area
- 106 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
171 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 435.159
- Has use
- medication
Show 4 more facts
- chemical formula
- C₂₄H₂₂FN₃O₄
- Commons category
- Exatecan
- isomeric SMILES
- CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C5[C@H](CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O
- canonical SMILES
- CCC1(C2=C(COC1=O)C(=O)N3CC4=C5C(CCC6=C5C(=CC(=C6C)F)N=C4C3=C2)N)O
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
Exatecan is a drug which is a structural analog of camptothecin with antineoplastic activity.
A derivative is used in Trastuzumab deruxtecan.
Excerpted from Wikipedia’s “exatecan” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0