fentiazac
Sign in to saveAlso known as Fentiazaco, Fentiazacum, 4-(p-Chlorophenyl)-2-phenyl-5-thiazoleacetic acid, 4-(4-Chlorophenyl)-2-phenyl-5-thiazoleacetic acid
Fentiazac is a thiazole-based nonsteroidal anti-inflammatory drug (NSAID) developed for use in joint and muscular pain. Like most other NSAIDs, it acts through inhibition of prostaglandin synthesis, via non-selective inhibition of both COX-1 and COX-2. First described in 1974, it was synthesized using the Hantzsch thiazole synthesis.
In the Vinony graph
Vinony's link graph records 285 inbound references to fentiazac, and connects out to salicylic acid, non-steroidal anti-inflammatory drug and metamizole sodium.
It sits within the topics 4-Chlorophenyl compounds, Acetic acids and Chemical pages without DrugBank identifier.
Vinony links it to 7 Wikipedia language editions.
Research
58 papers- Fentiazac in the treatment of osteoarthritis and tendinitis.Current medical research and opinion · 1983
- Metabolism of fentiazac.Arzneimittel-Forschung · 1980
- Fentiazac in rheumatoid arthritis: comparison with sulindac and long-term tolerance.Current medical research and opinion · 1983
- Fentiazac as a therapeutic aid in the treatment of tuberculosis.The Journal of international medical research · 1977
- Fentiazac in osteoarthritis: comparison of BID and QID regimens.Clinical therapeutics · 1983
via PubMed
Wikidata facts
- Mass
- 329.028
Show 4 more facts
- chemical formula
- C₁₇H₁₂ClNO₂S
- canonical SMILES
- C1=CC=C(C=C1)C2=NC(=C(S2)CC(=O)O)C3=CC=C(C=C3)Cl
- MCN code
- 2934.10.10
- Commons category
- Fentiazac
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Fentiazac is a thiazole-based nonsteroidal anti-inflammatory drug (NSAID) developed for use in joint and muscular pain. Like most other NSAIDs, it acts through inhibition of prostaglandin synthesis, via non-selective inhibition of both COX-1 and COX-2. First described in 1974, it was synthesized using the Hantzsch thiazole synthesis.
Fentiazac was marketed under the trade-name Norvedan (among others), but its market status is currently unknown and assumed to be discontinued.
Excerpted from Wikipedia’s “fentiazac” article, available under the CC BY-SA 4.0 licence.
Available in 7 languages
via Wikidata sitelinks · CC0