FGF1

Name

fibroblast growth factor 1

Type

protein-coding

Position

142,592,166–142,698,070 (−)

Aliases

AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1

Ensembl

ENSG00000113578

RefSeq RNA

NM_000800.5, NM_001144892.3, NM_001144934.2, NM_001144935.2, NM_001257205.1

RefSeq protein

NP_000791.1, NP_001138364.1, NP_001138406.1, NP_001138407.1, NP_001244134.1

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009].

via MyGene.info

Gene · Ensembl

fibroblast growth factor 1

Symbol

FGF1

Biotype

Protein coding

Organism

Homo sapiens

Location

5:142,592,163-142,698,070

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein FGF1 PDB 1afc.png

via Wikidata · CC0