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GeneQ14889334· pop 6

Also known as AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA

REDIRECT Fibroblast growth factor 1

Gene data

FGF1
Name
fibroblast growth factor 1
Type
protein-coding
Position
142,592,163–142,698,070 (−)
Aliases
AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1
RefSeq RNA
NM_000800.5, NM_001144892.3, NM_001144934.2, NM_001144935.2, NM_001257205.1
RefSeq protein
NP_000791.1, NP_001138364.1, NP_001138406.1, NP_001138407.1, NP_001244134.1

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Jan 2009].

via MyGene.info

Gene · Ensembl

fibroblast growth factor 1

Symbol
FGF1
Biotype
Protein coding
Organism
Homo sapiens
Location
5:142,592,163-142,698,070
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Image
Protein FGF1 PDB 1afc.png
Show 9 more facts
HomoloGene ID
625
genetic association
hypertrophic cardiomyopathy
found in taxon
Homo sapiens
genomic end
142077617
genomic start
141971743
cytogenetic location
5q31.3
expressed in
olfactory bulb
Sources (8)

via Wikidata · CC0

~1 min read

Encyclopedic overview

REDIRECT Fibroblast growth factor 1

Excerpted from Wikipedia’s “FGF1” article, available under the CC BY-SA 4.0 licence.

Available in 6 languages

via Wikidata sitelinks · CC0