FGF6
Sign in to saveAlso known as HBGF-6, HST2, fibroblast growth factor 6
Fibroblast growth factor 6 is a protein that in humans is encoded by the FGF6 gene.
In the Vinony graph
Within Vinony's link graph, FGF6 is referenced by 363 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Its subject is documented across 5 Wikipedia language editions.
Gene data
FGF6- Name
- fibroblast growth factor 6
- Type
- protein-coding
- Position
- 4,428,155–4,445,816 (−)
- Aliases
- HBGF-6, HST2
- Ensembl
- ENSG00000111241
- RefSeq RNA
- NM_020996.3, XM_017018995.2, XM_017018996.2, XM_054371412.1, XM_054371413.1
- RefSeq protein
- NP_066276.2, XP_016874484.1, XP_016874485.1, XP_054227387.1, XP_054227388.1
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
fibroblast growth factor 6
- Symbol
- FGF6
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:4,428,155-4,445,816
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/2251
- HomoloGene ID
- 10870
- genomic end
- 4445815
- genomic start
- 4537321
- chromosome
- human chromosome 12
- cytogenetic location
- 12p13.32
- expressed in
- urinary bladder
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Fibroblast growth factor 6 is a protein that in humans is encoded by the FGF6 gene.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene displayed oncogenic transforming activity when transfected into mammalian cells. The mouse homolog of this gene exhibits a restricted expression profile predominantly in the myogenic lineage, which suggested a role in muscle regeneration or differentiation.
Excerpted from Wikipedia’s “FGF6” article, available under the CC BY-SA 4.0 licence.