FGF17

Also known as FGF-13, HH20, FGF-17, fibroblast growth factor 17

Fibroblast growth factor 17 is a protein that in humans is encoded by the FGF17 gene.

Gene data

FGF17

Name: fibroblast growth factor 17
Type: protein-coding
Aliases: FGF-13, FGF-17, HH20

This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].

via MyGene.info

Gene · Ensembl

fibroblast growth factor 17

Symbol: FGF17
Biotype: Protein coding
Organism: Homo sapiens
Location: 8:22,042,388-22,048,809
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

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HomoloGene ID: 2872
exact match: identifiers.org/ncbigene/8822
genomic end: 21906320
genomic start: 21899909
cytogenetic location: 8p21.3

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Fibroblast growth factor 17 is a protein that in humans is encoded by the FGF17 gene.

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes, including embryonic development cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene was shown to be prominently expressed in the cerebellum and cortex. The mouse homolog of this gene was localized to specific sites in the midline structures of the forebrain, the midbrain-hindbrain junction, developing skeleton and developing arteries, which suggests a role in central nervous system, bone and vascular development. This gene was referred to as FGF-13 in reference 2, however, its amino acid sequence and chromosomal localization are identical to FGF17.