FGF10

Also known as fibroblast growth factor 10

Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene. It is a polypeptide of 208 amino acids. Human FGF10 gene is highly homologous (95.6%) to rat FGF10, where it was first discovered.

Gene data

FGF10

Name: fibroblast growth factor 10
Type: protein-coding
Aliases: LADD3

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008].

via MyGene.info