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GeneQ17927902· pop 5· linked from 383 articles

Also known as fibroblast growth factor 10

Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene. It is a polypeptide of 208 amino acids. Human FGF10 gene is highly homologous (95.6%) to rat FGF10, where it was first discovered.

Gene data

FGF10
Name
fibroblast growth factor 10
Type
protein-coding
Position
44,300,247–44,389,977 (−)
Aliases
LADD3
RefSeq RNA
NM_004465.2, XM_005248264.5
RefSeq protein
NP_004456.1, XP_005248321.1

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

fibroblast growth factor 10

Symbol
FGF10
Biotype
Protein coding
Organism
Homo sapiens
Location
5:44,300,247-44,389,977
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Image
Protein FGF10 PDB 1nun.png
Show 8 more facts
HomoloGene ID
3284
genomic start
44300247
genetic association
LADD syndrome
found in taxon
Homo sapiens
genomic end
44389808
cytogenetic location
5p12
Sources (6)

via Wikidata · CC0

~4 min read

Encyclopedic overview

8 sections
Contents
  • Function
  • Clinical significance
  • Animal studies
  • Interactions
  • See also
  • References
  • Further reading
  • External links

Fibroblast growth factor 10 is a protein that in humans is encoded by the FGF10 gene. It is a polypeptide of 208 amino acids. Human FGF10 gene is highly homologous (95.6%) to rat FGF10, where it was first discovered.

== Function ==

Excerpted from Wikipedia’s “FGF10” article, available under the CC BY-SA 4.0 licence.

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