GNB1

Name

G protein subunit beta 1

Type

protein-coding

Position

1,785,285–1,892,292 (−)

Aliases

HG2A, MDS, MRD42

Ensembl

ENSG00000078369

RefSeq RNA

NM_001282538.2, NM_001282539.2, NM_002074.5, XM_017001059.3, XM_017001060.3

RefSeq protein

NP_001269467.1, NP_001269468.1, NP_002065.1, XP_016856548.1, XP_016856549.1

Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. This gene encodes a beta subunit. Beta subunits are important regulators of alpha subunits, as well as of certain signal transduction receptors and effectors. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].