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halothane

Structure via PubChem · Public domain (PubChem)

EntityQ32921· pop 43· linked from 2,738 articles

Also known as 2-bromo-2-chloro-1,1,1-trifluoroethane, 2,2,2-trifluoro-1-chloro-1-bromoethane, 1-bromo-1-chloro-2,2,2-trifluoroethane, 1,1,1-trifluoro-2-chloro-2-bromoethane, 1,1,1-trifluoro-2-bromo-2-chloroethane, bromochlorotrifluoroethane

Halothane (bromochlorotrifluoroethane), sold under the brand name Fluothane among others, is a halocarbon with the chemical formula . It is used as a general anaesthetic given by inhalation. It can be used to induce or maintain anaesthesia. Its use in developed countries has been mostly replaced by newer anesthetic agents such as sevoflurane. One of its benefits is that it does not increase the production of saliva, which can be particularly useful in those who are difficult to intubate.

OverviewAI-generated

Halothane is a chemical compound with the formula C₂HBrClF₃. Its IUPAC name is 2-bromo-2-chloro-1,1,1-trifluoroethane. The substance has a molecular weight of 197.38 and a density of 1.87. It melts at -180 and boils at 122. The vapor pressure is 243, while its solubility is 0.3.

The compound has a global warming potential of 50. Its ceiling exposure limit is 16.2. Structural data indicates a charge of 0, with three hydrogen bond acceptors and no hydrogen bond donors. The topological polar surface area is 0, and the xlogp value is 2.3.

Synthesized by Vinony from 26 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Key facts

Drug.verifiedrevid
443852402
Drug.image
2-bromo-2-chloro-1,1,1-trifluoroethane 200.svg
Drug.image_class
skin-invert-image
Drug.width
120
Drug.image2
Halothane-3D-vdW.png
Drug.image_class2
bg-transparent
Drug.width2
120
Drug.tradename
Fluothane, Somnothane, Rhodialothan
Drug.DailyMedID
Halothane
Drug.routes_of_administration
Inhalation
Drug.class
Volatile anesthetic
Drug.ATC_prefix
N01
Drug.ATC_suffix
AB01
Drug.legal_BR
C1
Drug.legal_US
Rx-only
Drug.metabolism
Hepatic (CYP2E1)
Drug.excretion
Kidney, respiratory
Drug.CAS_number
151-67-7

via Wikipedia infobox

Chemical data

Formula
C2HBrClF3
Molecular weight
197.38 g/mol
IUPAC name
2-bromo-2-chloro-1,1,1-trifluoroethane
SMILES
C(C(F)(F)F)(Cl)Br
InChIKey
BCQZXOMGPXTTIC-UHFFFAOYSA-N
XLogP
2.3
Polar surface area
0 Ų
H-bond donors
0
H-bond acceptors
3
Formal charge
0

via PubChem

Research

19,814 papers

via PubMed

Gallery (11)