halothane

Also known as 2-bromo-2-chloro-1,1,1-trifluoroethane, 2,2,2-trifluoro-1-chloro-1-bromoethane, 1-bromo-1-chloro-2,2,2-trifluoroethane, 1,1,1-trifluoro-2-chloro-2-bromoethane, 1,1,1-trifluoro-2-bromo-2-chloroethane, bromochlorotrifluoroethane

groupe de stréréoisomères

Key facts

Drug.verifiedrevid: 443852402
Drug.image: 2-bromo-2-chloro-1,1,1-trifluoroethane 200.svg
Drug.image_class: skin-invert-image
Drug.width: 120
Drug.image2: Halothane-3D-vdW.png
Drug.image_class2: bg-transparent
Drug.width2: 120
Drug.tradename: Fluothane, Somnothane, Rhodialothan
Drug.DailyMedID: Halothane
Drug.routes_of_administration: Inhalation
Drug.class: Volatile anesthetic
Drug.ATC_prefix: N01
Drug.ATC_suffix: AB01
Drug.legal_BR: C1
Drug.legal_US: Rx-only
Drug.metabolism: Hepatic (CYP2E1)
Drug.excretion: Kidney, respiratory
Drug.CAS_number: 151-67-7

via Wikipedia infobox

Chemical data

Formula: C2HBrClF3
Molecular weight: 197.38 g/mol
IUPAC name: 2-bromo-2-chloro-1,1,1-trifluoroethane
SMILES: C(C(F)(F)F)(Cl)Br
InChIKey: BCQZXOMGPXTTIC-UHFFFAOYSA-N
XLogP: 2.3
Polar surface area: 0 Å²
H-bond donors: 0
H-bond acceptors: 3
Formal charge: 0

via PubChem

Research

19,814 papers

Halothane hepatitis: what's new?Drugs · 1980
Halothane hepatitis. Current concepts.Postgraduate medicine · 1974
The halothane hepatitis that was not.British journal of anaesthesia · 2020
Halothane hepatitis: a model of immune mediated drug hepatotoxicity.Clinical science (London, England : 1979) · 1987
Halothane hepatitis and the anaesthesiologist.South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde · 1984

via PubMed

Wikidata facts

Mass: 195.890224

Show 13 more facts

chemical formula: C₂HBrClF₃
melting point: -180
NIOSH Pocket Guide ID: 0310
density: 1.87
boiling point: 122
vapor pressure: 243
solubility: 0.3
ceiling exposure limit: 16.2
World Health Organisation international non-proprietary name: 氟烷
Commons category: Halothane
canonical SMILES: C(C(F)(F)F)(Cl)Br
MCN code: 2903.79.31
global warming potential: 50

Sources (10)

via Wikidata · CC0

Article · Français

L’halothane est un agent anesthésique volatil halogéné de la famille des haloalcanes utilisable pour l'induction et l'entretien des anesthésies générales. Sa toxicité cardiaque et hépatique, responsable de la survenue d'hépatites fulminantes, l'a fait pratiquement abandonner en anesthésie humaine, sauf dans les pays en développement où il reste employé en raison de son faible coût.

Abstract from DBpedia / Wikipedia · CC BY-SA