Structure via PubChem · Public domain (PubChem)
haloxazolam
Sign in to saveHaloxazolam (marketed in Japan under the brand name Somelin), is a drug which is a benzodiazepine derivative. It has similar hypnotic properties as the benzodiazepine drugs triazolam, temazepam, and flunitrazepam and as such is indicated for the treatment of insomnia. A study in cats comparing estazolam and haloxazolam found that haloxazolam only affects gamma motor neurons, whereas estazolam affects both alpha and gamma motor neurons.
In the Vinony graph
Within Vinony's link graph, haloxazolam is referenced by 574 other articles, and connects out to benzodiazepine drug, isovaleric acid and allopregnanolone.
It sits within the topics 2-Fluorophenyl compounds, Bromoarenes and Drugboxes which contain changes to verified fields.
Its subject is documented across 11 Wikipedia language editions.
Chemical data
- Formula
- C17H14BrFN2O2
- Molecular weight
- 377.2 g/mol
- IUPAC name
- 10-bromo-11b-(2-fluorophenyl)-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
- SMILES
- C1COC2(N1CC(=O)NC3=C2C=C(C=C3)Br)C4=CC=CC=C4F
- InChIKey
- XDKCGKQHVBOOHC-UHFFFAOYSA-N
- XLogP
- 2.8
- Polar surface area
- 41.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 376.022
Show 3 more facts
- chemical formula
- C₁₇H₁₄BrFN₂O₂
- canonical SMILES
- C1COC2(N1CC(=O)NC3=C2C=C(C=C3)Br)C4=CC=CC=C4F
- Commons category
- Haloxazolam
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Haloxazolam (marketed in Japan under the brand name Somelin), is a drug which is a benzodiazepine derivative. It has similar hypnotic properties as the benzodiazepine drugs triazolam, temazepam, and flunitrazepam and as such is indicated for the treatment of insomnia. A study in cats comparing estazolam and haloxazolam found that haloxazolam only affects gamma motor neurons, whereas estazolam affects both alpha and gamma motor neurons.
== See also == Benzodiazepine
Excerpted from Wikipedia’s “haloxazolam” article, available under the CC BY-SA 4.0 licence.