HOMER2

Also known as ACPD, CPD, HOMER-2, VESL-2, DFNA68, homer scaffolding protein 2, homer scaffold protein 2

Homer protein homolog 2 is a protein that in humans is encoded by the HOMER2 gene.

In the Vinony graph

Within Vinony's link graph, HOMER2 is referenced by 5 other articles, and connects out to PubMed, human chromosome 15 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 15.

Its subject is documented across 6 Wikipedia language editions.

Gene data

HOMER2

Name: homer scaffold protein 2
Type: protein-coding
Position: 82,834,664–82,986,153 (−)
Aliases: ACPD, CPD, DFNA68, HOMER-2, VESL-2
Ensembl: ENSG00000103942
RefSeq RNA: NM_004839.4, NM_199330.3, NM_199331.2, NM_199332.2, XM_005272449.5
RefSeq protein: NP_004830.2, NP_955362.1, XP_005272506.1, XP_006720838.1, XP_006720839.1

This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein is a postsynaptic density scaffolding protein. Alternative splicing results in multiple transcript variants. Two related pseudogenes have been identified on chromosome 14. [provided by RefSeq, Jun 2011].

Pathways

FoxO signaling pathway - Homo sapiens (human)Glutamatergic synapse - Homo sapiens (human)Neuronal System Neuronal System Neurexins and neuroligins Neurexins and neuroligins Protein-protein interactions at synapses Protein-protein interactions at synapses

via MyGene.info

Gene · Ensembl

homer scaffold protein 2

Symbol: HOMER2
Biotype: Protein coding
Organism: Homo sapiens
Location: 15:82,834,664-82,986,153
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene
Image: Protein HOMER2 PDB 1i7a.png

Show 7 more facts

HomoloGene ID: 3560
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/9455
genomic end: 83654661
genomic start: 83509838
chromosome: human chromosome 15
cytogenetic location: 15q25.2

Sources (3)

via Wikidata · CC0

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Encyclopedic overview

4 sections

Contents

Interactions
See also
References
Further reading

Homer protein homolog 2 is a protein that in humans is encoded by the HOMER2 gene.

This gene encodes a member of the homer family of dendritic proteins. Members of this family regulate group 1 metabotrophic glutamate receptor function. The encoded protein may be involved in cell growth. Four transcript variants encoding distinct isoforms have been identified for this gene.

Excerpted from Wikipedia’s “HOMER2” article, available under the CC BY-SA 4.0 licence.