INPP4B

Also known as inositol polyphosphate-4-phosphatase type II B

Inositol polyphosphate-4-phosphatase, type II, 105kDa is a protein that in humans is encoded by the INPP4B gene.

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Vinony's link graph records 3 inbound references to INPP4B, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.

It is catalogued under topics including EC 3.1.3 and Genes on human chromosome 4.

Vinony links it to 7 Wikipedia language editions.

Gene data

INPP4B

Name: inositol polyphosphate-4-phosphatase type II B
Type: protein-coding

INPP4B encodes the inositol polyphosphate 4-phosphatase type II, one of the enzymes involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

inositol polyphosphate-4-phosphatase type II B

Symbol: INPP4B
Biotype: Protein coding
Organism: Homo sapiens
Location: 4:142,023,160-142,847,432
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 20832
genetic association: ALS
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/8821
genomic end: 143768585
genomic start: 142944313
chromosome: human chromosome 4
cytogenetic location: 4q31.21

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Encyclopedic overview

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Inositol polyphosphate-4-phosphatase, type II, 105kDa is a protein that in humans is encoded by the INPP4B gene.

INPP4B encodes the inositol polyphosphate 4-phosphatase type II, a dual specificity phosphatase. INPP4B is involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate and phosphate groups from phosphotyrosines. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme.

Excerpted from Wikipedia’s “INPP4B” article, available under the CC BY-SA 4.0 licence.