INPP5A

Also known as 5PTASE, inositol polyphosphate-5-phosphatase A

Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene.

In the Vinony graph

Within Vinony's link graph, INPP5A is referenced by 2 other articles, and connects out to PubMed, human chromosome 10 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 10.

Its subject is documented across 5 Wikipedia language editions.

Gene data

INPP5A

Name: inositol polyphosphate-5-phosphatase A
Type: protein-coding
Position: 132,537,766–132,783,480 (+)
Aliases: 5PTASE
Ensembl: ENSG00000068383
RefSeq RNA: NM_001321042.2, NM_005539.5, XM_017016204.2, XM_017016205.2, XM_054365796.1
RefSeq protein: NP_001307971.1, NP_005530.3, XP_016871693.1, XP_016871694.1, XP_054221771.1

The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. [provided by RefSeq, Jul 2008].

Pathways

Inositol phosphate metabolism - Homo sapiens (human)Phosphatidylinositol signaling system - Homo sapiens (human)Insulin signaling pathway - Homo sapiens (human)Metabolism Inositol phosphate metabolism Synthesis of IP2, IP, and Ins in the cytosol

via MyGene.info

Gene · Ensembl

inositol polyphosphate-5-phosphatase A

Symbol: INPP5A
Biotype: Protein coding
Organism: Homo sapiens
Location: 10:132,537,766-132,783,480
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 4045
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/3632
genomic end: 134596979
genomic start: 132537787
chromosome: human chromosome 10
cytogenetic location: 10q26.3
expressed in: gastric mucosa

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

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Contents

References
Further reading

Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene.

The protein encoded by this gene is a membrane-associated type I inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase. InsP3 5-phosphatases hydrolyze Ins (1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

Excerpted from Wikipedia’s “INPP5A” article, available under the CC BY-SA 4.0 licence.