KRT83
Sign in to saveAlso known as HB3, Hb-3, KRTHB3, keratin 83, MNLIX, EKVP5
Keratin 83, also known as KRT83, is a protein which humans is encoded by the KRT83 gene.
In the Vinony graph
Within Vinony's link graph, KRT83 is referenced by 328 other articles, and connects out to hair keratin, PubMed and human chromosome 12.
It is catalogued under the topic Genes on human chromosome 12.
Its subject is documented across 5 Wikipedia language editions.
Gene data
KRT83- Name
- keratin 83
- Type
- protein-coding
- Position
- 52,314,301–52,321,398 (−)
- Aliases
- EKVP5, HB3, Hb-3, KRTHB3, MNLIX, MNLIX3
- Ensembl
- ENSG00000170523
- RefSeq RNA
- NM_002282.3
- RefSeq protein
- NP_002273.3
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
keratin 83
- Symbol
- KRT83
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:52,314,301-52,321,398
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 68248
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3889
- genomic end
- 52715182
- genomic start
- 52708085
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.13
- genetic association
- monilethrix
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Keratin 83, also known as KRT83, is a protein which humans is encoded by the KRT83 gene.
== Function == The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1 (KRT81), KRTHB3 (KRT83, this protein), and KRTHB6 (KRT86), is highly related. The other less-related subfamily includes KRTHB2 (KRT82), KRTHB4 (KRT84), and KRTHB5 (KRT85). All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB1 and KRTHB6, is found primarily in the hair cortex.
Excerpted from Wikipedia’s “KRT83” article, available under the CC BY-SA 4.0 licence.