KRT80
Sign in to saveAlso known as KB20, keratin 80
Keratin 80, also known as KRT80, is a protein which in humans is encoded by the KRT80 gene.
Gene data
KRT80- Name
- keratin 80
- Type
- protein-coding
- Aliases
- KB20
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.[provided by RefSeq, Oct 2010].
via MyGene.info
Gene · Ensembl
keratin 80
- Symbol
- KRT80
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:52,168,996-52,192,311
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 66610
- exact match
- identifiers.org/ncbigene/144501
- genomic end
- 52192014
- genomic start
- 52562780
- cytogenetic location
- 12q13.13
Sources (4)
via Wikidata · CC0
~1 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Keratin 80, also known as KRT80, is a protein which in humans is encoded by the KRT80 gene.
==Function== Keratins, such as KRT80, are filament proteins that make up one of the major structural fibers of epithelial cells.