KRT80
Sign in to saveAlso known as KB20, keratin 80
Keratin 80, also known as KRT80, is a protein which in humans is encoded by the KRT80 gene.
In the Vinony graph
Vinony's link graph records 271 inbound references to KRT80, and connects out to hair keratin, PubMed and human chromosome 12.
It is catalogued under the topic Genes on human chromosome 12.
Vinony links it to 5 Wikipedia language editions.
Gene data
KRT80- Name
- keratin 80
- Type
- protein-coding
- Position
- 52,168,996–52,192,311 (−)
- Aliases
- KB20
- Ensembl
- ENSG00000167767
- RefSeq RNA
- NM_001081492.2, NM_182507.3, XM_005268676.4, XM_054371193.1
- RefSeq protein
- NP_001074961.1, NP_872313.2, XP_005268733.1, XP_054227168.1
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.[provided by RefSeq, Oct 2010].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
keratin 80
- Symbol
- KRT80
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:52,168,996-52,192,311
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 66610
- exact match
- identifiers.org/ncbigene/144501
- genomic end
- 52192014
- genomic start
- 52562780
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.13
- expressed in
- Human penis
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Keratin 80, also known as KRT80, is a protein which in humans is encoded by the KRT80 gene.
==Function== Keratins, such as KRT80, are filament proteins that make up one of the major structural fibers of epithelial cells.
Excerpted from Wikipedia’s “KRT80” article, available under the CC BY-SA 4.0 licence.