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GeneQ18028463· pop 6· linked from 382 articles

Also known as CD107a, LAMPA, LGP120, lysosomal associated membrane protein 1

Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34).

Gene data

LAMP1
Name
lysosome associated membrane protein 1
Type
protein-coding
Aliases
CD107a, LAMPA, LGP120

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

lysosomal associated membrane protein 1

Symbol
LAMP1
Biotype
Protein coding
Organism
Homo sapiens
Location
13:113,297,088-113,324,413
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 6 more facts
HomoloGene ID
4061
genomic end
113977987
genomic start
113297239
cytogenetic location
13q34
Commons category
Lysosomal-associated membrane protein 1
Sources (5)

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~5 min read

Article

7 sections
Contents
  • Structure
  • Function
  • Role in cancer
  • See also
  • References
  • Further reading
  • External links

Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34).

thumb|328px|Immunofluorescence staining of HeLa | HeLa Cells with antibody to reveal lysosomal LAMP1 in red and [[vimentin containing intermediate filaments in green. Nuclear DNA is seen in blue. Antibodies and image courtesy EnCor Biotechnology Inc.]]

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