LAMP1
Sign in to saveAlso known as CD107a, LAMPA, LGP120, lysosomal associated membrane protein 1
Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34).
Gene data
LAMP1- Name
- lysosome associated membrane protein 1
- Type
- protein-coding
- Position
- 113,297,088–113,324,413 (+)
- Aliases
- CD107a, LAMPA, LGP120
- Ensembl
- ENSG00000185896
- RefSeq RNA
- NM_001445942.1, NM_005561.4, XM_011537494.3, XM_047430302.1, XM_054374518.1
- RefSeq protein
- NP_001432871.1, NP_005552.3, XP_011535796.1, XP_047286258.1, XP_054230493.1
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
lysosomal associated membrane protein 1
- Symbol
- LAMP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 13:113,297,088-113,324,413
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 4061
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3916
- genomic end
- 113977987
- genomic start
- 113297239
- chromosome
- human chromosome 13
- cytogenetic location
- 13q34
- Commons category
- Lysosomal-associated membrane protein 1
via Wikidata · CC0
~5 min read
Encyclopedic overview
7 sectionsContents
- Structure
- Function
- Role in cancer
- See also
- References
- Further reading
- External links
Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 gene. The human LAMP1 gene is located on the long arm (q) of chromosome 13 at region 3, band 4 (13q34).
thumb|328px|Immunofluorescence staining of HeLa | HeLa Cells with antibody to reveal lysosomal LAMP1 in red and [[vimentin containing intermediate filaments in green. Nuclear DNA is seen in blue. Antibodies and image courtesy EnCor Biotechnology Inc.]]
Excerpted from Wikipedia’s “LAMP1” article, available under the CC BY-SA 4.0 licence.