LDHA
Sign in to saveAlso known as GSD11, HEL-S-133P, LDH1, LDHM, PIG19, lactate dehydrogenase A
protein-coding gene in the species Homo sapiens
In the Vinony graph
Within Vinony's link graph, LDHA is referenced by 76 other articles, and connects out to PubMed, Ensembl genome database project and muscle.
It is catalogued under topics including Genes mutated in mice and Genes on human chromosome 11.
Its subject is documented across 5 Wikipedia language editions.
Gene data
LDHA- Name
- lactate dehydrogenase A
- Type
- protein-coding
- Position
- 18,394,347–18,408,425 (+)
- Aliases
- GSD11, HEL-S-133P, LDHM, PIG19
- Ensembl
- ENSG00000134333
- RefSeq RNA
- NM_001135239.2, NM_001165414.2, NM_001165415.2, NM_001165416.2, NM_005566.4
- RefSeq protein
- NP_001128711.1, NP_001158886.1, NP_001158887.1, NP_001158888.1, NP_005557.1
This gene encodes the A subunit of lactate dehydrogenase enzyme which catalyzes the reversible conversion of pyruvate to lactate with the concomitant oxidation of NADH to NAD in anaerobic glycolysis. The protein is found predominantly in skeletal muscle and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. The human genome contains several non-transcribed pseudogenes of this gene. [provided by RefSeq, Sep 2023].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
lactate dehydrogenase A
- Symbol
- LDHA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 11:18,394,347-18,408,425
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein LDHA PDB 1i10.png
Show 8 more facts
- HomoloGene ID
- 56495
- genomic end
- 18408425
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/3939
- genomic start
- 18394560
- chromosome
- human chromosome 11
- cytogenetic location
- 11p15.1
- expressed in
- gastrocnemius muscle
Sources (7)
via Wikidata · CC0