MAPRE2

Also known as EB1, EB2, RP1, CSCSC2, microtubule associated protein RP/EB family member 2

Microtubule-associated protein RP/EB family member 2 is a protein that in humans is encoded by the MAPRE2 gene.

In the Vinony graph

Within Vinony's link graph, MAPRE2 is referenced by 273 other articles, and connects out to PubMed, human chromosome 18 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 18.

Its subject is documented across 5 Wikipedia language editions.

Gene data

MAPRE2

Name: microtubule associated protein RP/EB family member 2
Type: protein-coding
Position: 34,976,928–35,143,470 (+)
Aliases: CSCSC2, EB1, EB2, RP1
Ensembl: ENSG00000166974
RefSeq RNA: NM_001143826.3, NM_001143827.3, NM_001256420.2, NM_014268.4, NR_046177.2
RefSeq protein: NP_001137298.1, NP_001137299.1, NP_001243349.1, NP_055083.1

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012].