Also known as GIF, GLIF, MMIF, macrophage migration inhibitory factor (glycosylation-inhibiting factor), macrophage migration inhibitory factor
protein-coding gene in the species Homo sapiens
Gene data
MIF- Name
- macrophage migration inhibitory factor
- Type
- protein-coding
- Position
- 23,894,372–23,895,227 (+)
- Aliases
- GIF, GLIF, MMIF
- Ensembl
- ENSG00000276701
- RefSeq RNA
- NM_002415.2
- RefSeq protein
- NP_002406.1
This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
macrophage migration inhibitory factor
- Symbol
- MIF
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR22_1_CTG7:130,366-131,589
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein MIF PDB 1ca7.png
Show 6 more facts
- HomoloGene ID
- 55655
- exact match
- identifiers.org/ncbigene/4282
- genomic start
- 23894383
- genomic end
- 24237414
- cytogenetic location
- 22q11.23
- Commons category
- Macrophage migration inhibitory factor
via Wikidata · CC0