MIF

Also known as GIF, GLIF, MMIF, macrophage migration inhibitory factor (glycosylation-inhibiting factor), macrophage migration inhibitory factor

protein-coding gene in the species Homo sapiens

Gene data

MIF

Name: macrophage migration inhibitory factor
Type: protein-coding
Position: 23,894,372–23,895,227 (+)
Aliases: GIF, GLIF, MMIF
Ensembl: ENSG00000276701
RefSeq RNA: NM_002415.2
RefSeq protein: NP_002406.1

This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008].