MKLN1

Also known as TWA2, muskelin 1

Muskelin is a protein that in humans is encoded by the MKLN1 gene.

In the Vinony graph

Vinony's link graph records 4 inbound references to MKLN1, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.

Vinony files it under Genes on human chromosome 7 and Kelch proteins.

Vinony links it to 5 Wikipedia language editions.

Gene data

MKLN1

Name: muskelin 1
Type: protein-coding
Position: 131,110,096–131,496,632 (+)
Aliases: TWA2
Ensembl: ENSG00000128585
RefSeq RNA: NM_001145354.2, NM_001321316.2, NM_013255.5, XM_006715993.4, XM_011516224.4
RefSeq protein: NP_001138826.1, NP_001308245.1, NP_037387.2, XP_006716056.1, XP_011514526.1

Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008].

Pathways

Aerobic respiration and respiratory electron transport Metabolism Pyruvate metabolism Regulation of pyruvate metabolism Ciliary landscape

via MyGene.info

Gene · Ensembl

muskelin 1

Symbol: MKLN1
Biotype: Protein coding
Organism: Homo sapiens
Location: 7:131,110,096-131,496,632
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 8305
genetic association: asthma
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/4289
chromosome: human chromosome 7
genomic start: 130794855
genomic end: 131496632
cytogenetic location: 7q32.3

Sources (5)

via Wikidata · CC0

~4 min read

Encyclopedic overview

7 sections

Contents

Gene
Protein
CTLH complex
Species distribution
Clinical significance
References
Further reading

Muskelin is a protein that in humans is encoded by the MKLN1 gene.

== Gene == In humans, the MKLN1 gene is located on the long arm of chromosome 7 (7q32.3). It produces 12 splice variant transcripts, 6 of which are translated into a protein product. It is widely expressed across human tissues.

Excerpted from Wikipedia’s “MKLN1” article, available under the CC BY-SA 4.0 licence.