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GeneQ18037081· pop 6· linked from 50 articles

NCAPD3

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Also known as CAP-D3, CAPD3, hCAP-D3, hHCP-6, hcp-6, non-SMC condensin II complex subunit D3, MCPH22

Condensin-2 complex subunit D3 (CAP-D3) also known as non-SMC condensin II complex subunit D3 (NCAPD3) is a protein that, in humans, is encoded by the NCAPD3 gene. CAP-D3 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

Gene data

NCAPD3
Name
non-SMC condensin II complex subunit D3
Type
protein-coding
Position
134,149,039–134,225,504 (−)
Aliases
CAP-D3, CAPD3, MCPH22, hCAP-D3, hHCP-6, hcp-6
Ensembl
ENSG00000151503
RefSeq RNA
NM_001372065.1, NM_001372068.1, NM_001372069.1, NM_001372070.1, NM_015261.3
RefSeq protein
NP_001358994.1, NP_001358997.1, NP_001358998.1, NP_001358999.1, NP_056076.1

Condensin complexes I and II play essential roles in mitotic chromosome assembly and segregation. Both condensins contain 2 invariant structural maintenance of chromosome (SMC) subunits, SMC2 (MIM 605576) and SMC4 (MIM 605575), but they contain different sets of non-SMC subunits. NCAPD3 is 1 of 3 non-SMC subunits that define condensin II (Ono et al., 2003 [PubMed 14532007]).[supplied by OMIM, Mar 2008].

Gene Ontology

Pathways

Cell CycleCondensation of Prophase ChromosomesMitotic ProphaseM PhaseCell Cycle, Mitotic

via MyGene.info

Gene · Ensembl

non-SMC condensin II complex subunit D3

Symbol
NCAPD3
Biotype
Protein coding
Organism
Homo sapiens
Location
11:134,149,039-134,225,504
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
41021
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/23310
genomic end
134225504
genomic start
134150113
chromosome
human chromosome 11
cytogenetic location
11q25
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections
Contents
  • References
  • Further reading

Condensin-2 complex subunit D3 (CAP-D3) also known as non-SMC condensin II complex subunit D3 (NCAPD3) is a protein that, in humans, is encoded by the NCAPD3 gene. CAP-D3 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

==References==

Excerpted from Wikipedia’s “NCAPD3” article, available under the CC BY-SA 4.0 licence.

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via Wikidata sitelinks · CC0