Also known as IKBB, TRIP9, NFKB inhibitor beta
NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene.
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jul 2011].
Biological process
~1 min read
NF-kappa-B inhibitor beta is a protein that in humans is encoded by the NFKBIB gene.
== Function ==
Molecular function
via MyGene.info
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).