NFKBIE
Sign in to saveAlso known as IKBE, NFKB inhibitor epsilon
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, also known as NFKBIE, is a protein which in humans is encoded by the NFKBIE gene.
Gene data
NFKBIE- Name
- NFKB inhibitor epsilon
- Type
- protein-coding
- Aliases
- IKBE
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. [provided by RefSeq, Sep 2011].
via MyGene.info
Gene · Ensembl
NFKB inhibitor epsilon
- Symbol
- NFKBIE
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:44,258,166-44,265,788
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 36160
- exact match
- identifiers.org/ncbigene/4794
- genomic end
- 44233500
- genomic start
- 44225903
- cytogenetic location
- 6p21.1
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon, also known as NFKBIE, is a protein which in humans is encoded by the NFKBIE gene.
== Function ==