NXT1

Also known as MTR2, P15, nuclear transport factor 2 like export factor 1

NTF2-related export protein 1 is a protein that in humans is encoded by the NXT1 gene.

Gene data

NXT1

Name: nuclear transport factor 2 like export factor 1
Type: protein-coding
Aliases: MTR2, P15

The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

nuclear transport factor 2 like export factor 1

Symbol: NXT1
Biotype: Protein coding
Organism: Homo sapiens
Location: 20:23,350,148-23,354,771
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein NXT1 PDB 1jkg.png

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HomoloGene ID: 8301
exact match: identifiers.org/ncbigene/29107
genomic end: 23354771
genomic start: 23350791
cytogenetic location: 20p11.21

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NTF2-related export protein 1 is a protein that in humans is encoded by the NXT1 gene.

The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene.