NFE2
Sign in to saveAlso known as NF-E2, p45, nuclear factor, erythroid 2
__NOTOC__ Transcription factor NF-E2 45 kDa subunit is a protein that in humans is encoded by the NFE2 gene.
In the Vinony graph
Within Vinony's link graph, NFE2 is referenced by 815 other articles, and connects out to PubMed, human chromosome 12 and homeobox.
Vinony files it under Genes on human chromosome 12, Human proteins and Transcription factors.
Its subject is documented across 6 Wikipedia language editions.
Gene data
NFE2- Name
- nuclear factor, erythroid 2
- Type
- protein-coding
- Position
- 54,292,107–54,301,259 (−)
- Aliases
- NF-E2, p45
- Ensembl
- ENSG00000123405
- RefSeq RNA
- NM_001136023.3, NM_001261461.2, NM_001400365.1, NM_001400372.1, NM_001400373.1
- RefSeq protein
- NP_001129495.1, NP_001248390.1, NP_001387294.1, NP_001387301.1, NP_001387302.1
Enables several functions, including WW domain binding activity; identical protein binding activity; and protein N-terminus binding activity. Contributes to cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including labyrinthine layer blood vessel development; negative regulation of bone mineralization; and negative regulation of syncytium formation by plasma membrane fusion. Part of protein-DNA complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
nuclear factor, erythroid 2
- Symbol
- NFE2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:54,292,107-54,301,259
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein NFE2 PDB 1LVX.png
Show 7 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 4491
- exact match
- identifiers.org/ncbigene/4778
- genomic end
- 54301015
- genomic start
- 54685895
- chromosome
- human chromosome 12
- cytogenetic location
- 12q13.13
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Interactions
- References
- Further reading
- External links
__NOTOC__ Transcription factor NF-E2 45 kDa subunit is a protein that in humans is encoded by the NFE2 gene.
It is involved in megakaryocyte production.
Excerpted from Wikipedia’s “NFE2” article, available under the CC BY-SA 4.0 licence.