E2F3
Sign in to saveAlso known as E2F-3, E2F transcription factor 3
Transcription factor E2F3 is a protein that in humans is encoded by the E2F3 gene.
Gene data
E2F3- Name
- E2F transcription factor 3
- Type
- protein-coding
- Aliases
- E2F-3
This gene encodes a member of a small family of transcription factors that function through binding of DP interaction partner proteins. The encoded protein recognizes a specific sequence motif in DNA and interacts directly with the retinoblastoma protein (pRB) to regulate the expression of genes involved in the cell cycle. Altered copy number and activity of this gene have been observed in a number of human cancers. There are pseudogenes for this gene on chromosomes 2 and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2013].
via MyGene.info
Gene · Ensembl
E2F transcription factor 3
- Symbol
- E2F3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:20,401,840-20,493,714
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- exact match
- identifiers.org/ncbigene/1871
- HomoloGene ID
- 74413
- genomic end
- 20493714
- genomic start
- 20401879
- cytogenetic location
- 6p22.3
Sources (3)
via Wikidata · CC0
~1 min read
Article
6 sectionsContents
- Function
- Interactions
- See also
- References
- Further reading
- External links
Transcription factor E2F3 is a protein that in humans is encoded by the E2F3 gene.
== Function ==