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GeneQ18051192· pop 5· linked from 4 articles

E2F7

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Also known as E2F transcription factor 7

Transcription factor E2F7 is a protein that in humans is encoded by the E2F7 gene.

In the Vinony graph

Vinony's link graph records 4 inbound references to E2F7, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 12.

Vinony links it to 5 Wikipedia language editions.

Gene data

E2F7

Name: E2F transcription factor 7
Type: protein-coding
Position: 77,021,245–77,065,579 (−)
Ensembl: ENSG00000165891
RefSeq RNA: NM_203394.3, XM_011537966.3, XM_011537969.3, XM_054371191.1, XM_054371192.1
RefSeq protein: NP_976328.2, XP_011536268.1, XP_011536271.1, XP_054227166.1, XP_054227167.1

E2F transcription factors, such as E2F7, play an essential role in the regulation of cell cycle progression (Di Stefano et al., 2003 [PubMed 14633988]).[supplied by OMIM, May 2008]

Gene Ontology

Biological process

negative regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II placenta development placenta development sprouting angiogenesis sprouting angiogenesis regulation of DNA-templated transcription regulation of transcription by RNA polymerase II

Molecular function

RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific cis-regulatory region sequence-specific DNA binding DNA-binding transcription repressor activity DNA-binding transcription repressor activity

Cellular component

chromatin nucleus nucleoplasm nucleoplasm transcription regulator complex RNA polymerase II transcription regulator complex

Pathways

Adaptive Immune System Immune System Generic Transcription Pathway Transcriptional Regulation by TP53 TP53 Regulates Transcription of Cell Cycle Genes TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest RNA Polymerase II Transcription Gene expression (Transcription)Somatic hypermutation of immunoglobulin genes Immunoglobulin maturation

via MyGene.info

Gene · Ensembl

E2F transcription factor 7

Symbol: E2F7
Biotype: Protein coding
Organism: Homo sapiens
Location: 12:77,021,245-77,065,579
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 18685
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/144455
genomic end: 77065569
genomic start: 77021248
chromosome: human chromosome 12
cytogenetic location: 12q21.2

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

Transcription factor E2F7 is a protein that in humans is encoded by the E2F7 gene.

==References==

Excerpted from Wikipedia’s “E2F7” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 12