EEF2

Also known as EEF-2, EF-2, EF2, SCA26, eukaryotic translation elongation factor 2, Eukaryotic elongation factor 2

Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic counterpart of bacterial EF-G.

Gene data

EEF2

Name: eukaryotic translation elongation factor 2
Type: protein-coding
Position: 3,976,044–3,985,479 (−)
Aliases: EEF-2, EF-2, EF2, SCA26
Ensembl: ENSG00000167658
RefSeq RNA: NM_001961.4
RefSeq protein: NP_001952.1

This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008].

Pathways

AMPK signaling pathway - Homo sapiens (human)Oxytocin signaling pathway - Homo sapiens (human)Eukaryotic Translation Elongation Eukaryotic Translation Elongation Peptide chain elongation Peptide chain elongation Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation Disease Innate Immune System

via MyGene.info

Gene · Ensembl

eukaryotic translation elongation factor 2

Symbol: EEF2
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:3,976,044-3,985,479
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts

HomoloGene ID: 134867
exact match: identifiers.org/ncbigene/1938
genomic end: 3985463
genomic start: 3976054
cytogenetic location: 19p13.3

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Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic counterpart of bacterial EF-G.

This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the ribosome. This protein is completely inactivated by EF-2 kinase phosphorylation.