EEF2

Also known as EEF-2, EF-2, EF2, SCA26, eukaryotic translation elongation factor 2, Eukaryotic elongation factor 2

Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic counterpart of bacterial EF-G.

Gene data

EEF2

Name: eukaryotic translation elongation factor 2
Type: protein-coding
Position: 3,976,044–3,985,479 (−)
Aliases: EEF-2, EF-2, EF2, SCA26
Ensembl: ENSG00000167658
RefSeq RNA: NM_001961.4
RefSeq protein: NP_001952.1

This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

response to ischemia skeletal muscle contraction translation

Article

3 sections

Contents

References
Further reading
External links

Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic counterpart of bacterial EF-G.

This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the ribosome. This protein is completely inactivated by EF-2 kinase phosphorylation.