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GeneQ18040351· pop 5· linked from 3 articles

ETV7

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Also known as TEL-2, TEL2, TELB, ETS variant 7, ETS variant transcription factor 7

Transcription factor ETV7 is a protein that in humans is encoded by the ETV7 gene.

In the Vinony graph

Within Vinony's link graph, ETV7 is referenced by 3 other articles, and connects out to PubMed, human chromosome 6 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 6.

Its subject is documented across 5 Wikipedia language editions.

Gene data

ETV7

Name: ETS variant transcription factor 7
Type: protein-coding
Position: 36,352,630–36,387,801 (−)
Aliases: TEL-2, TEL2, TELB
Ensembl: ENSG00000010030
RefSeq RNA: NM_001207035.2, NM_001207036.2, NM_001207037.2, NM_001207038.2, NM_001207039.2
RefSeq protein: NP_001193964.1, NP_001193965.1, NP_001193966.1, NP_001193967.1, NP_001193968.1

The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011].

Gene Ontology

Biological process

negative regulation of transcription by RNA polymerase II regulation of DNA-templated transcription regulation of transcription by RNA polymerase II regulation of transcription by RNA polymerase II transcription by RNA polymerase II animal organ morphogenesis cell differentiation

Molecular function

RNA polymerase II transcription regulatory region sequence-specific DNA binding RNA polymerase II transcription regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription repressor activity, RNA polymerase II-specific DNA-binding transcription factor activity protein binding

Cellular component

chromatin nucleus nucleus nucleus nucleoplasm

Pathways

Transcriptional misregulation in cancer - Homo sapiens (human)

via MyGene.info

Gene · Ensembl

ETS variant transcription factor 7

Symbol: ETV7
Biotype: Protein coding
Organism: Homo sapiens
Location: 6:36,352,630-36,387,801
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 8 more facts

HomoloGene ID: 56746
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/51513
cytogenetic location: 6p21.31
genomic end: 36356164
genomic start: 36322419
chromosome: human chromosome 6
expressed in: granulocyte

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

References
Further reading
External links

Transcription factor ETV7 is a protein that in humans is encoded by the ETV7 gene.

==References==

Excerpted from Wikipedia’s “ETV7” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 6