NFIX

Also known as MRSHSS, NF1A, SOTOS2, nuclear factor I X, NF1-X, NF-I/X, CTF, MALNS

Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. NFI-X3, a splice variant of NFIX, regulates Glial fibrillary acidic protein and YKL-40 in astrocytes.

Gene data

NFIX

Name: nuclear factor I X
Type: protein-coding
Aliases: CTF, MALNS, MRSHSS, NF-I/X, NF1-X, NF1A, SOTOS2

The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2012].

via MyGene.info

Gene · Ensembl

nuclear factor I X

Symbol: NFIX
Biotype: Protein coding
Organism: Homo sapiens
Location: 19:12,995,401-13,098,796
Strand: Forward (+)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

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HomoloGene ID: 1872
genomic end: 13098796
exact match: identifiers.org/ncbigene/4784
genomic start: 12995475
cytogenetic location: 19p13.13

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Nuclear factor 1 X-type is a protein that in humans is encoded by the NFIX gene. NFI-X3, a splice variant of NFIX, regulates Glial fibrillary acidic protein and YKL-40 in astrocytes.

== Interactions == Nfix has been shown to interact with SKI protein and it is also known to interact with AP-1. NFI-X3 has been shown to interact with STAT3.