P3H4

Also known as NO55, NOL55, SC65, LEPREL4, prolyl 3-hydroxylase family member 4 (non-enzymatic), prolyl 3-hydroxylase family member 4 (inactive)

Endoplasmic reticulum protein SC65, also known as Leprecan-like protein 4 (LEPREL4) or nucleolar autoantigen No55, is a protein that in humans is encoded by the P3H4 gene.

In the Vinony graph

Within Vinony's link graph, P3H4 is referenced by 1 other article, and connects out to chromosome, PubMed and human chromosome 17.

It is catalogued under the topic Genes on human chromosome 17.

Its subject is documented across 6 Wikipedia language editions.

Gene data

P3H4

Name: prolyl 3-hydroxylase family member 4 (inactive)
Type: protein-coding
Position: 41,801,944–41,812,750 (−)
Aliases: LEPREL4, NO55, NOL55, SC65
Ensembl: ENSG00000141696
RefSeq RNA: NM_006455.3, XM_006721640.5, XM_047435137.1, XM_047435138.1, XM_054314723.1
RefSeq protein: NP_006446.1, XP_006721703.2, XP_047291093.1, XP_047291094.1, XP_054170698.1

This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

synaptonemal complex assembly peptidyl-lysine hydroxylation collagen fibril organization collagen fibril organization collagen fibril organization collagen biosynthetic process collagen biosynthetic process bone remodeling

Molecular function

collagen binding

Cellular component

condensed nuclear chromosome synaptonemal complex synaptonemal complex nucleolus endoplasmic reticulum endoplasmic reticulum endoplasmic reticulum catalytic complex

via MyGene.info

Gene · Ensembl

prolyl 3-hydroxylase family member 4 (inactive)

Symbol: P3H4
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:41,801,944-41,812,750
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 4713
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/10609
chromosome: human chromosome 17
genomic start: 39958199
genomic end: 39968856
cytogenetic location: 17q21.2

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

Function
References
Further reading

Endoplasmic reticulum protein SC65, also known as Leprecan-like protein 4 (LEPREL4) or nucleolar autoantigen No55, is a protein that in humans is encoded by the P3H4 gene.

== Function ==

Excerpted from Wikipedia’s “P3H4” article, available under the CC BY-SA 4.0 licence.