PDCD5
Sign in to saveAlso known as TFAR19, programmed cell death 5
Programmed cell death protein 5 is a protein, originally identified as an apoptosis-accelerating protein, that in humans is encoded by the PDCD5 gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to PDCD5, and connects out to PubMed, human chromosome 19 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 19.
Vinony links it to 7 Wikipedia language editions.
Gene data
PDCD5- Name
- programmed cell death 5
- Type
- protein-coding
- Position
- 32,581,062–32,587,453 (+)
- Aliases
- TFAR19
- Ensembl
- ENSG00000105185
- RefSeq RNA
- NM_004708.4, XM_005259392.6, XM_054322581.1
- RefSeq protein
- NP_004699.1, XP_005259449.1, XP_054178556.1
This gene encodes a protein that is upregulated during apoptosis where it translocates rapidly from the cytoplasm to the nucleus. The encoded protein may be an important regulator of K(lysine) acetyltransferase 5 (a protein involved in transcription, DNA damage response and cell cycle control) by inhibiting its proteasome-dependent degradation. Pseudogenes have been identified on chromosomes 5 and 12 [provided by RefSeq, Dec 2010].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
programmed cell death 5
- Symbol
- PDCD5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:32,581,062-32,587,453
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PDCD5 PDB 2cru.png
Show 8 more facts
- HomoloGene ID
- 10506
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9141
- chromosome
- human chromosome 19
- genomic start
- 32581190
- genomic end
- 32587453
- cytogenetic location
- 19q13.11
- expressed in
- anterior cingulate cortex
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Programmed cell death protein 5 is a protein, originally identified as an apoptosis-accelerating protein, that in humans is encoded by the PDCD5 gene.
This gene encodes a protein expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli. Prior to apoptosis induction, this gene product is distributed in both the nucleus and cytoplasm.
Excerpted from Wikipedia’s “PDCD5” article, available under the CC BY-SA 4.0 licence.