PEMT
Sign in to saveAlso known as PEAMT, PEMPT, PEMT2, PNMT, phosphatidylethanolamine N-methyltransferase, PLMT
protein-coding gene in the species Homo sapiens
Gene data
PEMT- Name
- phosphatidylethanolamine N-methyltransferase
- Type
- protein-coding
- Aliases
- PEAMT, PEMPT, PEMT2, PLMT
Phosphatidylcholine (PC) is the most abundant mammalian phospholipid. This gene encodes an enzyme which converts phosphatidylethanolamine to phosphatidylcholine by sequential methylation in the liver. Another distinct synthetic pathway in nucleated cells converts intracellular choline to phosphatidylcholine by a three-step process. The protein isoforms encoded by this gene localize to the endoplasmic reticulum and mitochondria-associated membranes. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012].
via MyGene.info
Gene · Ensembl
phosphatidylethanolamine N-methyltransferase
- Symbol
- PEMT
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:17,505,559-17,592,105
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 6291
- exact match
- identifiers.org/ncbigene/10400
- genomic end
- 17495022
- genomic start
- 17408877
- cytogenetic location
- 17p11.2
Sources (3)
via Wikidata · CC0