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เพทิดีน

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EntityQ55434· pop 43· linked from 2,255 articles

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Also known as meperidine

Pethidine, also known as meperidine and sold under the brand name Demerol among others, is a fully synthetic opioid pain medication of the phenylpiperidine class. Synthesized in 1938 as a potential anticholinergic agent by the German chemist Otto Eisleb, its analgesic properties were first recognized by Otto Schaumann while working for IG Farben, in Germany. Pethidine is the prototype of a large family of analgesics including the pethidine 4-phenylpiperidines (e.g., piminodine, anileridine), the prodines (e.g., alphaprodine, MPPP), bemidones (e.g., ketobemidone), and others more distant, inclu

OverviewAI-generated

Pethidine is a chemical compound with the IUPAC name ethyl 1-methyl-4-phenylpiperidine-4-carboxylate. Its chemical formula is C₁₅H₂₁NO₂, and it has a molecular weight of 247.33. The substance possesses a charge of 0, an xlogp value of 2.5, and a topological polar surface area of 29.5. It contains three hydrogen bond acceptors and no hydrogen bond donors.

The compound is identified by the MCN code 2933.33.81. In scientific literature, pethidine is the subject of 8,226 PubMed entries. It is also referenced by 2,255 other encyclopedia articles.

Synthesized by Vinony from 18 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.

Chemical data

Formula
C15H21NO2
Molecular weight
247.33 g/mol
IUPAC name
ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
SMILES
CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2
InChIKey
XADCESSVHJOZHK-UHFFFAOYSA-N
XLogP
2.5
Polar surface area
29.5 Ų
H-bond donors
0
H-bond acceptors
3
Formal charge
0

via PubChem

Research

8,226 papers

via PubMed

Wikidata facts

Has part
hydrogen
Mass
247.157229
Manufacturer
Pfizer
Has use
medication
Show 6 more facts
MCN code
2933.33.81
chemical formula
C₁₅H₂₁NO₂
significant drug interaction
clozapine
Commons category
Pethidine
canonical SMILES
CCOC(=O)C1(CCN(CC1)C)C2=CC=CC=C2
medical condition treated
pain
Sources (5)

via Wikidata · CC0

Gallery (12)

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