PRG4

Name

proteoglycan 4

Type

protein-coding

Position

186,296,270–186,314,567 (+)

Aliases

CACP, HAPO, JCAP, MSF, SZP

Ensembl

ENSG00000116690

RefSeq RNA

NM_001127708.3, NM_001127709.3, NM_001127710.3, NM_001303232.2, NM_005807.6

RefSeq protein

NP_001121180.2, NP_001121181.2, NP_001121182.2, NP_001290161.1, NP_005798.3

The protein encoded by this gene is a large proteoglycan that is synthesized by chondrocytes located at the surface of articular cartilage and by some synovial lining cells. This protein contains both chondroitin sulfate and keratan sulfate glycosaminoglycans. It functions as a boundary lubricant at the cartilage surface and contributes to the elastic absorption and energy dissipation of synovial fluid. Mutations in this gene result in camptodactyly-arthropathy-coxa vara-pericarditis syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].

via MyGene.info

Gene · Ensembl

proteoglycan 4

Symbol

PRG4

Biotype

Protein coding

Organism

Homo sapiens

Location

1:186,296,222-186,314,567

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0