PURB
Sign in to saveAlso known as PURBETA, purine-rich element binding protein B, purine rich element binding protein B
Transcriptional activator protein Pur-beta is a protein that in humans is encoded by the PURB gene.
In the Vinony graph
Within Vinony's link graph, PURB is referenced by 2 other articles, and connects out to PubMed, human chromosome 7 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 7.
Its subject is documented across 7 Wikipedia language editions.
Gene data
PURB- Name
- purine rich element binding protein B
- Type
- protein-coding
- Position
- 44,876,299–44,885,530 (−)
- Aliases
- PURBETA
- Ensembl
- ENSG00000146676
- RefSeq RNA
- NM_033224.5
- RefSeq protein
- NP_150093.1
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
purine rich element binding protein B
- Symbol
- PURB
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:44,876,299-44,885,530
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 69087
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/5814
- genomic end
- 44885530
- genomic start
- 44876299
- chromosome
- human chromosome 7
- cytogenetic location
- 7p13
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Transcriptional activator protein Pur-beta is a protein that in humans is encoded by the PURB gene.
This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans.
Excerpted from Wikipedia’s “PURB” article, available under the CC BY-SA 4.0 licence.