RARA

Name

retinoic acid receptor alpha

Type

protein-coding

Position

40,309,180–40,357,643 (+)

Aliases

NR1B1, RAR, RARalpha

Ensembl

ENSG00000131759

RefSeq RNA

NM_000964.4, NM_001024809.4, NM_001033603.1, NM_001145301.3, NM_001145302.3

RefSeq protein

NP_000955.1, NP_001019980.1, NP_001138773.1, NP_001138774.1, XP_005257609.1

This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010].