RFC1

Name

replication factor C subunit 1

Type

protein-coding

Position

39,287,456–39,366,395 (−)

Aliases

A1, CANVAS, MHCBFB, PO-GA, RECC1, RFC, RFC140

Ensembl

ENSG00000035928

RefSeq RNA

NM_001204747.2, NM_001363495.2, NM_001363496.2, NM_002913.5, XM_011513731.2

RefSeq protein

NP_001191676.1, NP_001350424.1, NP_001350425.1, NP_002904.3, XP_011512033.1

This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Mar 2011].

via MyGene.info

Gene · Ensembl

replication factor C subunit 1

Symbol

RFC1

Biotype

Protein coding

Organism

Homo sapiens

Location

4:39,287,455-39,366,400

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Image

Protein RFC1 PDB 2EBU.png

via Wikidata · CC0