SYT2

Also known as SytII, CMS7, MYSPC, synaptotagmin 2, CMS7A, CMS7B

Synaptotagmin-2 is a protein that in humans is encoded by the SYT2 gene.

Gene data

SYT2

Name: synaptotagmin 2
Type: protein-coding
Position: 202,590,596–202,710,526 (−)
Aliases: CMS7, CMS7A, CMS7B, MYSPC, SytII
Ensembl: ENSG00000143858
RefSeq RNA: NM_001136504.1, NM_177402.5, XM_011509192.3, XM_017000309.3, XM_017000310.3
RefSeq protein: NP_001129976.1, NP_796376.2, XP_011507494.1, XP_016855798.1, XP_016855799.1

This gene encodes a synaptic vesicle membrane protein. The encoded protein is thought to function as a calcium sensor in vesicular trafficking and exocytosis. Mutations in this gene are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014].