TLR10

Name

toll like receptor 10

Type

protein-coding

Position

38,772,238–38,782,990 (−)

Aliases

CD290

Ensembl

ENSG00000174123

RefSeq RNA

NM_001017388.3, NM_001195106.2, NM_001195107.2, NM_001195108.2, NM_030956.4

RefSeq protein

NP_001017388.1, NP_001182035.1, NP_001182036.1, NP_001182037.1, NP_112218.2

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is most highly expressed in lymphoid tissues such as spleen, lymph node, thymus, and tonsil. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2010].

via MyGene.info

Gene · Ensembl

toll like receptor 10

Symbol

TLR10

Biotype

Protein coding

Organism

Homo sapiens

Location

4:38,772,238-38,782,990

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

PBB Protein TLR10 image.jpg

via Wikidata · CC0