VPS18
Sign in to saveAlso known as PEP3, VPS18, CORVET/HOPS core subunit, VPS18 core subunit of CORVET and HOPS complexes
Vacuolar protein sorting-associated protein 18 homolog is a protein that in humans is encoded by the VPS18 gene.
In the Vinony graph
Within Vinony's link graph, VPS18 is referenced by 4 other articles, and connects out to PubMed, human chromosome 15 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 15.
Its subject is documented across 5 Wikipedia language editions.
Gene data
VPS18- Name
- VPS18 core subunit of CORVET and HOPS complexes
- Type
- protein-coding
- Position
- 40,894,412–40,903,975 (+)
- Aliases
- PEP3
- Ensembl
- ENSG00000104142
- RefSeq RNA
- NM_020857.3, XM_011521843.3, XM_054378541.1
- RefSeq protein
- NP_065908.1, XP_011520145.1, XP_054234516.1
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
VPS18 core subunit of CORVET and HOPS complexes
- Symbol
- VPS18
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:40,894,412-40,903,975
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 13302
- genomic end
- 41196173
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/57617
- genomic start
- 40894450
- expressed in
- white blood cell
- chromosome
- human chromosome 15
- cytogenetic location
- 15q15.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Vacuolar protein sorting-associated protein 18 homolog is a protein that in humans is encoded by the VPS18 gene.
== Function ==
Excerpted from Wikipedia’s “VPS18” article, available under the CC BY-SA 4.0 licence.