VPS52

Also known as ARE1, SAC2, SACM2L, dJ1033B10.5, VPS52, GARP complex subunit, VPS52 subunit of GARP complex

Vacuolar protein sorting-associated protein 52 homolog is a protein that in humans is encoded by the VPS52 gene.

Gene data

VPS52

Name: VPS52 subunit of GARP complex
Type: protein-coding
Position: 33,250,272–33,272,047 (−)
Aliases: ARE1, SAC2, SACM2L, dJ1033B10.5
Ensembl: ENSG00000223618
RefSeq RNA: NM_001289174.2, NM_001289175.1, NM_001289176.1, NM_022553.6, XM_011514797.2
RefSeq protein: NP_001276103.1, NP_001276104.1, NP_001276105.1, NP_072047.4, XP_011513099.1

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014].

Gene Ontology

Biological process

protein targeting

Article

2 sections

Contents

References
Further reading

Vacuolar protein sorting-associated protein 52 homolog is a protein that in humans is encoded by the VPS52 gene.

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18.