VPS45
Sign in to saveAlso known as H1, H1VPS45, SCN5, VPS45A, VPS45B, VPS54A, VSP45, VSP45A
Vacuolar protein sorting-associated protein 45 is a protein that in humans is encoded by the VPS45 gene.
In the Vinony graph
Vinony's link graph records 3 inbound references to VPS45, and connects out to PubMed, vesicle and human chromosome 1.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 6 Wikipedia language editions.
Gene data
VPS45- Name
- vacuolar protein sorting 45 homolog
- Type
- protein-coding
- Position
- 150,067,279–150,145,329 (+)
- Aliases
- H1, H1VPS45, SCN5, VPS45A, VPS45B, VPS54A, VSP45, VSP45A
- Ensembl
- ENSG00000136631
- RefSeq RNA
- NM_001279353.2, NM_001279354.2, NM_001279355.1, NM_007259.5, NR_103998.2
- RefSeq protein
- NP_001266282.1, NP_001266283.1, NP_009190.2, XP_024308559.1, XP_054190019.1
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
vacuolar protein sorting 45 homolog
- Symbol
- VPS45
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:150,067,279-150,145,329
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 9 more facts
- genetic association
- VPS45
- HomoloGene ID
- 5250
- exact match
- identifiers.org/ncbigene/11311
- found in taxon
- Homo sapiens
- chromosome
- human chromosome 1
- genomic start
- 150067279
- genomic end
- 150145329
- cytogenetic location
- 1q21.2
- expressed in
- Achilles tendon
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Vacuolar protein sorting-associated protein 45 is a protein that in humans is encoded by the VPS45 gene.
== Function ==
Excerpted from Wikipedia’s “VPS45” article, available under the CC BY-SA 4.0 licence.