VPS29
Sign in to saveAlso known as DC15, PEP11, DC7, VPS29 retromer complex component, VPS29, retromer complex component
VPS29 is a human gene coding for the vacuolar protein sorting protein Vps29, a component of the retromer complex.
In the Vinony graph
Vinony's link graph records 2 inbound references to VPS29, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Vinony links it to 5 Wikipedia language editions.
Gene data
VPS29- Name
- VPS29 retromer complex component
- Type
- protein-coding
- Position
- 110,469,903–110,502,132 (−)
- Aliases
- DC15, DC7, PEP11
- Ensembl
- ENSG00000111237
- RefSeq RNA
- NM_001282150.2, NM_001282151.2, NM_016226.5, NM_057180.3, NR_104099.2
- RefSeq protein
- NP_001269079.1, NP_001269080.1, NP_057310.1, NP_476528.1
This gene belongs to a group of vacuolar protein sorting (VPS) genes that, when functionally impaired, disrupt the efficient delivery of vacuolar hydrolases. The protein encoded by this gene is a component of a large multimeric complex, termed the retromer complex, which is involved in retrograde transport of proteins from endosomes to the trans-Golgi network. This VPS protein may be involved in the formation of the inner shell of the retromer coat for retrograde vesicles leaving the prevacuolar compartment. Alternative splice variants encoding different isoforms and representing non-protein coding transcripts have been found for this gene. [provided by RefSeq, Aug 2013].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
VPS29 retromer complex component
- Symbol
- VPS29
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:110,469,903-110,502,132
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein VPS29 PDB 1w24.png
Show 7 more facts
- HomoloGene ID
- 9433
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/51699
- genomic end
- 110502111
- genomic start
- 110491083
- chromosome
- human chromosome 12
- cytogenetic location
- 12q24.11
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Yeast homolog
- Function
- References
- Further reading
VPS29 is a human gene coding for the vacuolar protein sorting protein Vps29, a component of the retromer complex.
==Yeast homolog== The homologous protein (one that performs the same function) in yeast is Vacuolar protein sorting 29 homolog (S. cerevisiae).
Excerpted from Wikipedia’s “VPS29” article, available under the CC BY-SA 4.0 licence.