WDR77
Sign in to saveAlso known as MEP-50, MEP50, Nbla10071, p44, p44/Mep50, HKMT1069, WD repeat domain 77
protein-coding gene in the species Homo sapiens
In the Vinony graph
Vinony's link graph records 7 inbound references to WDR77, and connects out to PubMed, human chromosome 1 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 1.
Vinony links it to 5 Wikipedia language editions.
Gene data
WDR77- Name
- WD repeat domain 77
- Type
- protein-coding
- Position
- 111,437,222–111,449,297 (−)
- Aliases
- HKMT1069, MEP-50, MEP50, Nbla10071, p44, p44/Mep50
- Ensembl
- ENSG00000116455
- RefSeq RNA
- NM_001317062.2, NM_001317063.2, NM_001317064.2, NM_024102.4, NR_133654.2
- RefSeq protein
- NP_001303991.1, NP_001303992.1, NP_001303993.1, NP_077007.1
The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
WD repeat domain 77
- Symbol
- WDR77
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:111,437,222-111,449,297
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 11466
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/79084
- genomic end
- 111449256
- genomic start
- 111982512
- chromosome
- human chromosome 1
- cytogenetic location
- 1p13.2
- expressed in
- rectum
Sources (3)
via Wikidata · CC0