XCL2
Sign in to saveAlso known as SCM-1b, SCM1B, SCYC2, chemokine (C motif) ligand 2, X-C motif chemokine ligand 2
Chemokine (C motif) ligand 2 (XCL2) is a small cytokine belonging to the XC chemokine family that is highly related to another chemokine called XCL1. It is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated cells. XCL2 induces chemotaxis of cells expressing the chemokine receptor XCR1. Its gene is located on chromosome 1 in humans.
Gene data
XCL2- Name
- X-C motif chemokine ligand 2
- Type
- protein-coding
- Aliases
- SCM-1b, SCM1B, SCYC2
Predicted to enable CCR chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; leukocyte chemotaxis; and positive regulation of T cell chemotaxis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]
via MyGene.info
Gene · Ensembl
X-C motif chemokine ligand 2
- Symbol
- XCL2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:168,540,765-168,544,113
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 130513
- exact match
- identifiers.org/ncbigene/6846
- genomic end
- 168513235
- genomic start
- 168540768
- cytogenetic location
- 1q24.2
via Wikidata · CC0
~1 min read
Article
1 sectionsContents
- References
Chemokine (C motif) ligand 2 (XCL2) is a small cytokine belonging to the XC chemokine family that is highly related to another chemokine called XCL1. It is predominantly expressed in activated T cells, but can also be found at low levels in unstimulated cells. XCL2 induces chemotaxis of cells expressing the chemokine receptor XCR1. Its gene is located on chromosome 1 in humans.
==References==