زینترول

Chemical data

Formula

C19H26N2O4S

Molecular weight

378.5 g/mol

IUPAC name

N-[2-hydroxy-5-[1-hydroxy-2-[(2-methyl-1-phenylpropan-2-yl)amino]ethyl]phenyl]methanesulfonamide

SMILES

CC(C)(CC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)NS(=O)(=O)C)O

InChIKey

XJBCFFLVLOPYBV-UHFFFAOYSA-N

XLogP

1.8

Polar surface area

107 Ų

H-bond donors

4

H-bond acceptors

6

Formal charge

0

via PubChem

Drug data · ChEMBL

Max clinical phase

Phase 2

Molecule type

Small molecule

via ChEMBL · EBI

• Beta 2-adrenoceptor activation by zinterol causes protein phosphorylation, contractile effects and relaxant effects through a cAMP pathway in human atrium.Molecular and cellular biochemistry · 1996
• Agonist effects of zinterol at the mouse and human beta(3)-adrenoceptor.Naunyn-Schmiedeberg's archives of pharmacology · 2006
• Effects of the beta-2 adrenergic agonist zinterol on DRL behavior and locomotor activity.Psychopharmacology · 1993
• Murine ventricular L-type Ca(2+) current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor.British journal of pharmacology · 2001
• Effect of the beta-2 adrenergic agonist zinterol on norepinephrine turnover.Research communications in chemical pathology and pharmacology · 1993

via PubMed

Wikidata facts

Subclass of

chemical compound

Mass

378.161328

via Wikidata · CC0