ampiroxicam

Also known as CP 65703, carbonic acid ethyl 1-({2-methyl-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl}oxy)ethyl ester S,S-dioxide, CP-65703

Ampiroxicam (INN) is a non-steroidal anti-inflammatory drug (NSAID). It is a prodrug of piroxicam. It has been studied for potential anticancer activity, but preliminary results did not show evidence of such activity.

In the Vinony graph

Vinony's link graph records 281 inbound references to ampiroxicam, and connects out to salicylic acid, non-steroidal anti-inflammatory drug and metamizole sodium.

Vinony files it under 2-Pyridyl compounds, Benzothiazines and Chemical pages without DrugBank identifier.

Vinony links it to 9 Wikipedia language editions.

Chemical data

Formula: C20H21N3O7S
Molecular weight: 447.5 g/mol
IUPAC name: ethyl 1-[[2-methyl-1,1-dioxo-3-(pyridin-2-ylcarbamoyl)-1lambda6,2-benzothiazin-4-yl]oxy]ethyl carbonate
SMILES: CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3
InChIKey: LSNWBKACGXCGAJ-UHFFFAOYSA-N
XLogP: 4
Polar surface area: 133 Å²
H-bond donors: 1
H-bond acceptors: 9
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 447.11

Show 4 more facts

chemical formula: C₂₀H₂₁N₃O₇S
canonical SMILES: CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3
World Health Organisation international non-proprietary name: ampiroxicam
Commons category: Ampiroxicam

Sources (2)

via Wikidata · CC0

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