AP2M1
Sign in to saveAlso known as AP50, CLAPM1, mu2, adaptor related protein complex 2 mu 1 subunit, adaptor related protein complex 2 subunit mu 1, MRD60
AP-2 complex subunit mu is a protein that in humans is encoded by the AP2M1 gene.
In the Vinony graph
Vinony's link graph records 86 inbound references to AP2M1, and connects out to PubMed, human chromosome 3 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 3.
Vinony links it to 8 Wikipedia language editions.
Gene data
AP2M1- Name
- adaptor related protein complex 2 subunit mu 1
- Type
- protein-coding
- Position
- 184,174,689–184,184,214 (+)
- Aliases
- AP50, CLAPM1, MRD60, mu2
- Ensembl
- ENSG00000161203
- RefSeq RNA
- NM_001025205.2, NM_001311198.2, NM_004068.4
- RefSeq protein
- NP_001020376.1, NP_001298127.1, NP_004059.2
This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
adaptor related protein complex 2 subunit mu 1
- Symbol
- AP2M1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:184,174,689-184,184,214
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein AP2M1 PDB 1bw8.png
Show 8 more facts
- HomoloGene ID
- 3000
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/1173
- genomic end
- 184184214
- genomic start
- 183892477
- chromosome
- human chromosome 3
- cytogenetic location
- 3q27.1
- expressed in
- ganglionic eminence
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
AP-2 complex subunit mu is a protein that in humans is encoded by the AP2M1 gene.
== Function ==
Excerpted from Wikipedia’s “AP2M1” article, available under the CC BY-SA 4.0 licence.
Available in 8 languages
via Wikidata sitelinks · CC0